Table 2.

PAH-albumin adducts and risk of HCC

PAH_Albumin	Cases		Controls		OR(95% CI)	OR*(95% CI)
	No.	%	No.	%
Non-detectable	89	51.2	409	52.7	1.0	1.0
Detectable	85	48.9	367	47.3	1.0(0.6-1.5)	0.9(0.5-1.4)
Below mean	93	53.5	467	60.1	1.0	1.0
Above mean	81	46.6	309	39.9	1.3(0.8-2.0)	1.1(0.7-1.8)
Quantile 1‡	97	55.8	501	64.6	1.0	1.0
Quantile 2	16	9.2	90	11.5	1.1(0.6-2.0)	1.0(0.5-2.0)
Quantile 3	23	13.2	93	12.0	1.5(0.8-2.8)	1.2(0.6-2.4)
Quantile 4	38	21.8	92	11.9	2.6†(1.3-5.3)**	2.0§(1.0-4.2)

^**:p value <0.01

^§: p<0.05

^†: p for linear trend<0.05

^*: adjusted for HBsAg status, habitual smoking, and alcohol drinking

^‡: Subjects with detectable adducts were quartiled and those in the lowest quartile combined with those with nondetectable adducts for Quantile 1