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. 1996 Nov 26;93(24):14020–14024. doi: 10.1073/pnas.93.24.14020

Figure 3.

Figure 3

Dark field autoradiograms comparing the effects of an excitotoxic lesions of the caudal hippocampus/entorhinal cortical area on the expression of glial fibrillary acidic protein (A) and PS-1 mRNA (B). Animals were sacrificed at either 3, 7, or 11 days postlesion. There was a marked loss of PS-1 mRNA within the bed of the lesion (arrows) after 7 days. This contrasts with the massive up-regulation of glial fibrillary acidic protein mRNA expression in adjacent sections.