SCC-1/COH-2 is expressed in dividing cells throughout the development. (A)
An L1 larva stained with anti-SCC-1/COH-2 antibodies (SCC-1/COH-2, red) and
Sytox Green (DNA, green). The SCC-1/COH-2 signal was intense in the 14
hypodermal V lineage cells, which divide synchronously. The magnified view
shows a cell at metaphase in which the SCC-1/COH-2 signal is dispersed in the
cytoplasm. Arrowheads indicate condensed chromosomes. Bar, 20 μm. (B) A
slightly older L1 larva, stained as described above. In addition to the
dividing P lineage and Q lineage cells, germ cells were stained specifically
with anti-SCC-1/COH-2 antibodies. Bar, 20 μm. (C) The ventral region of an
L3 larva. The SCC-1/COH-2 signal could be detected in 4 M lineage and 10 P
lineage cells, which divide concurrently. Bar, 10 μm.