Table 1.
Peptide immunoreactivity | Control | Agonist | Ca2+-free | Capsaicin des |
---|---|---|---|---|
Spinal cord (cinnamaldehyde, 10 μM) | ||||
SP-LI | 8.3 ± 1.7 | 160.5 ± 16.7* | 34.5 ± 9.7† | 23.7 ± 7.2† |
CGRP-LI | 38.5 ± 7.4 | 720.4 ± 43.7* | 118.5 ± 25.8† | 63.8 ± 10.8† |
Esophagus (cinnamaldehyde, 50 μM) | ||||
SP-LI | 2.4 ± 0.9 | 31.5 ± 8.2* | 6.3 ± 2.1† | 5.8 ± 1.9† |
CGRP-LI | 4.8 ± 1.3 | 93.2 ± 21.4* | 19.2 ± 4.6† | 17.8 ± 5.1† |
*, P < 0.05 versus control (vehicle);
†, P < 0.05 versus cinnamaldehyde, alone.
Each entry represents the mean ± SEM of at least four experiments.