Table 4.

Factors Associated with Inconsistent Preference Trajectories in Multivariable Analysis:

	WILLINGNESS TO UNDERGO HIGH BURDEN THERAPY TO AVOID DEATH	WILLINGNESS TO RISK PHYSICAL DISABILITY TO AVOID DEATH	WILLINGNESS TO RISK COGNITIVE DISABILITY TO AVOID DEATH
	Adjusted Odds Ratio (95% Confidence Interval)
Number of interviews	1.9 (1.5, 2.4)	1.7 (1.3, 2.2)	1.9 (1.5, 2.4)
Diagnosis
Cancer	1.0 (Reference)	1.0 (Reference)	1.0 (Reference)
COPD	2.0 (0.8, 5.4)	1.7 (0.7, 4.2)	2.5 (1.0, 6.1)
HF	1.5 (0.5, 4.1)	1.3 (0.5, 3.3)	1.7 (0.7, 4.4)
Inconsistent ADL trajectory	0.6 (0.2, 1.5)	1.1 (0.4, 2.5)	0.8 (0.3, 1.9)
Inconsistent SRH trajectory	1.5 (0.7, 3.4)	2.3 (1.0, 5.2)	--
Inconsistent QOL trajectory	--	--	1.8 (0.8, 3.8)
Initial preference at the extreme (wants therapy despite 99% chance of death/ 100% chance of disability)	0.5 (0.2, 1.0)	0.3 (0.1, 0.8)	0.6 (0.2, 2.0)

COPD = chronic obstructive pulmonary disease; HF = heart failure; ADL = activities of daily living; SRH = self-rated health; QOL = quality of life.