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. 2007 Jul 26;406(Pt 1):105–114. doi: 10.1042/BJ20061903

Table 2. A comparison of the effect of various inhibitors on NOX4 as well as on NOX2 and mitochondrial ROS generation.

Inhibitor NOX4 IC50 (μM) NOX2 IC50 (μM) Mitochondrial oxidase IC50 (μM)
DPI 0.2 0.9 [46] 5–10 [39]
0.2–0.5 [47]
Thioridazine 5 0.5–2 [28] 10 [41]
Apocynin 215 10 [29] >30 [48]
>300 [39]
Gliotoxin >100 3–10 [30] 0.3 [49]
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