Table 1.
Characteristics of Study Sample
| Variable | Women with hot flashes | Women without hot flashes | p-value | ||
|---|---|---|---|---|---|
| n | %* | n | %* | ||
| Sample Size | 372 | 58.2 | 267 | 41.8 | |
| Participant Characteristics | |||||
| Age (years) | |||||
| 45 to 49 | 219 | 58.9 | 194 | 72.7 | 0.001 |
| 50 to 54 | 153 | 41.1 | 73 | 27.3 | |
| Race | |||||
| White | 302 | 81.2 | 230 | 86.1 | 0.006 |
| Black | 66 | 17.7 | 28 | 10.5 | |
| Other | 3 | 0.8 | 8 | 2.9 | |
| Smoking Status | |||||
| Current | 42 | 11.3 | 16 | 6.0 | 0.006 |
| Former | 153 | 41.1 | 94 | 35.2 | |
| Never | 176 | 47.3 | 157 | 58.8 | |
| Body Mass Index (kg/m2) | |||||
| ≤24.9 | 146 | 39.2 | 127 | 47.6 | 0.002 |
| 25.0 to 29.9 | 94 | 25.3 | 81 | 30.3 | |
| ≥30.0 | 131 | 35.2 | 59 | 22.1 | |
| Genotype | |||||
| CYPc17α | |||||
| +/+ | 134 | 36.0 | 96 | 36.0 | 1.0 |
| +/− | 193 | 51.9 | 137 | 51.3 | |
| −/− | 45 | 12.1 | 34 | 12.7 | |
| 3βHSD | |||||
| +/+ | 53 | 14.2 | 54 | 20.2 | 0.06 |
| +/− | 161 | 43.3 | 122 | 45.7 | |
| −/− | 150 | 40.3 | 88 | 33.0 | |
| CYP19 | |||||
| +/+ | 118 | 31.7 | 81 | 30.3 | 0.6 |
| +/− | 181 | 48.7 | 125 | 46.8 | |
| −/− | 69 | 18.5 | 59 | 22.1 | |
| CYP1A1 | |||||
| +/+ | 291 | 78.2 | 209 | 78.3 | 1.0 |
| +/− | 75 | 20.2 | 54 | 20.2 | |
| −/− | 6 | 1.6 | 4 | 1.5 | |
| CYP1B1 | |||||
| +/+ | 87 | 23.4 | 77 | 28.8 | 0.3 |
| +/− | 180 | 48.4 | 122 | 45.7 | |
| −/− | 103 | 27.7 | 67 | 25.1 | |
| COMT | |||||
| +/+ | 98 | 26.3 | 67 | 25.1 | 0.1 |
| +/− | 205 | 55.1 | 131 | 49.1 | |
| −/− | 69 | 18.5 | 68 | 25.5 | |
*
Due to missing information, some columns do not add up to the total n listed, and percentages do not add up to 100.