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. Author manuscript; available in PMC: 2008 Jun 20.
Published in final edited form as: Maturitas. 2006 Dec 21;57(2):120–131. doi: 10.1016/j.maturitas.2006.11.009

Table 3.

Association between sex steroid hormone levels and hot flash variables

Testosterone Androstenedione DHEA-S Progesterone SHBG
Variable n Geometric Mean* (95% CI) p-value Geometric Mean* (95% CI) p-value Geometric Mean* (95% CI) p-value Geometric Mean* (95% CI) p-value Geometric Mean* (95% CI) p-value
Hot Flashes in the past 30 days
 Never 265 0.465 (0.433, 0.501) 0.9 2.026 (1.906, 2.155) 1.0 384.52 (358.17, 412.40) 0.8 1.017 (0.855, 1.210) 0.001 59.15 (55.48, 63.05) 0.03
 No (with ever hot flashes) 115 0.463 (0.415, 0.516) 2.040 (1.863, 2.234) 374.28 (337.31, 415.30) 0.858 (0.663, 1.110) 62.18 (56.54, 68.37)
 Yes 242 0.475 (0.439, 0.513) 2.012 (1.885, 2.147) 369.81 (343.44, 398.62) 0.603 (0.501, 0.725) 53.62 (50.10, 57.40)
Severity of Hot Flashes
 Never 265 0.465 (0.433, 0.501) 1.0 2.024 (1.904, 2.151) 0.9 384.14 (358.17, 411.99) 0.7 1.007 (0.846, 1.198) 0.003 58.97 (55.31, 62.93) 0.5
 Mild 132 0.470 (0.425, 0.521) 1.980 (1.818, 2.155) 376.15 (341.38, 414.88) 0.718 (0.564, 0.914) 56.04 (51.21, 61.31)
 Moderate/Severe 227 0.467 (0.432, 0.505) 2.034 (1.904, 2.171) 366.87 (340.36, 395.44) 0.652 (0.541, 0.785) 56.20 (52.46, 60.28)
Frequency of Hot Flashes
 Never 265 0.466 (0.433, 0.501) 0.5 2.030 (1.910, 2.158) 0.3 385.68 (359.60, 413.64) 0.6 1.020 (0.857, 1.213) 0.001 59.15 (55.48, 63.05) 0.003
 Monthly 158 0.483 (0.440, 0.529) 2.083 (1.929, 2.252) 376.91 (344.81, 411.99) 0.791 (0.634, 1.015) 63.05 (58.15, 68.37)
 At least weekly 178 0.447 (0.408, 0.489) 1.919 (1.777, 2.071) 363.58 (332.95, 396.63) 0.574 (0.462, 0.712) 51.78 (47.85, 56.04)
Duration of Hot Flashes
 Never 265 0.465 (0.432, 0.500) 0.9 2.026 (1.906, 2.153) 1.0 384.52 (358.53, 412.40) 0.2 1.005 (0.845, 1.196) 0.002 58.97 (55.32, 62.87) 0.2
 ≥ 1 year 233 0.463 (0.429, 0.501) 2.006 (1.879, 2.140) 359.24 (333.62, 386.84) 0.735 (0.611, 0.883) 57.69 (53.89, 61.74)
 < 1 year 117 0.480 (0.430, 0.534) 2.014 (1.839, 2.203) 400.61 (361.04, 444.08) 0.586 (0.453, 0.757) 53.20 (48.38, 58.44)
*

adjusted for age, race, smoking status, BMI, days since last menstrual period