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. Author manuscript; available in PMC: 2008 Aug 15.
Published in final edited form as: Virology. 2007 Apr 24;365(1):144–156. doi: 10.1016/j.virol.2007.02.035

Figure 1. WT SV5 and rSV5-EGFP are cytopathic in primary cultures of immature moDC.

Figure 1

A) Immature moDC from a representative donor were mock infected or infected at an moi of 5 with WT rSV5 or rSV5-EGFP. Phase-contrast and EGFP expression were visualized at 22 h pi. B) Immature moDC infected with the indicated viruses were analyzed by flow cytometry at 22 h pi for intracellular levels of activated caspase-3 and cell surface CD11c. z-VAD-FMK was included in one culture of infected DC at 100 uM. Numbers in the upper quadrant indicate the percent of CD11c+ cells that stained positive for cleaved caspase-3. Representative of three experiments.