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. Author manuscript; available in PMC: 2008 Aug 15.
Published in final edited form as: Virology. 2007 Apr 24;365(1):144–156. doi: 10.1016/j.virol.2007.02.035

Figure 2. Pan-caspase inhibitor decreases apoptosis in SV5 infected immature moDC, but results in only low levels of cell surface maturation markers.

Figure 2

Immature moDC were mock infected or infected at an moi of 5 with WT rSV5 and then treated with or without 100 uM z-VAD-FMK. Levels of intracellular cleaved caspase-3 (panel A) and the indicated cell surface maturation markers (panels B–D) were assayed by flow cytometry at 24 h pi. Cells treated with 200 ng/ml of LPS were used as a positive control. Results are the average of three experiments from three individual donors (with standard error bars). Results in panels B–D are expressed as a fold change relative to mock infected, mock treated sample set at 1.