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. Author manuscript; available in PMC: 2008 Aug 15.
Published in final edited form as: Virology. 2007 Apr 24;365(1):144–156. doi: 10.1016/j.virol.2007.02.035

Figure 5. Apoptotic markers in SV5 infected immature moDC are reduced by treatment with TLR-4 and -6 agonists.

Figure 5

Mock infected or WT rSV5 infected immature DC were treated at 7 h pi with the indicated TLR agonists as detailed in Materials and Methods. Cells were analyzed by flow cytometry at 22 h pi for levels of intracellular cleaved caspase-3 (panel A) or cell surface annexinV staining (panel B). Results are the mean values (with standard error bars) from three experiments with three individual donors. *, P values for percent active caspase-3 and annexin positive cells on TLR-4 agonist treated SV5 infected cells compared to untreated infected control cells were 0.007. #, P values for percent active caspase-3 and annexin positive cells on TLR-6 agonist treated infected cells compared to untreated infected control cells were 0.01 and 0.017, respectively.