Table 2. Characteristics of GAS Exogenous Elements.
M-type, Strain | Exogenous Element | Virulence Gene(s) | CDS Start | CDS Stop | Size (kbp) | Percent G+C | |
M1, SF370 | |||||||
370.1 | speC-spd1 | 0655 | 0712 | 40.9 | 39.3 | ||
370.2 | speH-speI | 0937 | 1008 | 42.5 | 38.0 | ||
370-RD.1 | srtA | 1075 | 1088 | 12.2 | 33.2 | ||
370.3 | spd3 | 1436 | 1488 | 33.5 | 38.0 | ||
370.4 | none* | 2122 | 2147 | 13.6 | 36.8 | ||
M1, MGAS5005 | |||||||
5005-RD.1 | srtA | 0797 | 0816 | 12.2 | 33.2 | ||
5005.1 | speA2 | 0995 | 1052 | 38.1 | 38.0 | ||
5005.2 | spd3 | 1168 | 1222 | 33.4 | 37.7 | ||
5005.3 | sda | 1414 | 1467 | 40.8 | 39.8 | ||
M2, MGAS10270 | |||||||
10270.1 | speC-spd1 | 0536 | 0598 | 44.1 | 38.0 | ||
10270.2 | spd3 | 0796 | 0853 | 37.9 | 38.2 | ||
10270-RD.1 | srtA | 0910 | 0932 | 17.5 | 31.9 | ||
10270.3 | speK-sla | 1297 | 1361 | 41.8 | 38.5 | ||
10270-RD.2 | R28 | 1378 | 1411 | 34.7 | 34.5 | ||
10270.4 | none | 1874 | 1896 | 14.3 | 36.9 | ||
10270.5 | none | 1917 | 1951 | 11.8 | 36.6 | ||
M3, MGAS315 | |||||||
315.1 | none | 0681 | 0736 | 39.5 | 37.8 | ||
315.2 | ssa | 0919 | 0978 | 41.1 | 38.3 | ||
315.3 | spd4 | 1094 | 1145 | 34.4 | 38.0 | ||
315.4 | speK-sla | 1203 | 1266 | 61.8 | 38.6 | ||
315.5 | speA3 | 1300 | 1354 | 38.2 | 38.0 | ||
315.6 | sdn | 1408 | 1458 | 40.0 | 39.7 | ||
M3, SSI-1 | |||||||
SPsP1 | sdn | 0408 | 0456 | 40.0 | 39.7 | ||
SPsP2 | speA3 | 0507 | 0561 | 38.2 | 38.1 | ||
SPsP3 | speK-sla | 0597 | 0659 | 41.8 | 38.6 | ||
SpsP4 | spd4 | 0717 | 0771 | 34.4 | 38.0 | ||
SPsP5 | none | 0877 | 0937 | 41.0 | 38.2 | ||
SPsP6 | ssa | 1118 | 1172 | 39.9 | 37.7 | ||
M4, MGAS10750 | |||||||
10750.1 | speC-spd1 | 0560 | 0622 | 43.8 | 38.0 | ||
10750.2 | spd3 | 0831 | 0889 | 37.9 | 38.3 | ||
10750-RD.1 | srtA | 0945 | 0967 | 17.6 | 31.9 | ||
10750.3 | ssa | 1276 | 1328 | 35.6 | 38.0 | ||
10750-RD.2 | erm(A) | 1679 | 1719 | 48.9 | 31.2 | ||
10750.4 | none | 1897 | 1921 | 13.9 | 35.2 | ||
M5, Manfredo | |||||||
man.1 | spd3 | 0471 | 0535 | 41.4 | 38.6 | ||
man.2 | spd4 | 0631 | 0692 | 36.0 | 37.9 | ||
man.3 | speH-speI | 1021 | 1070 | 39.9 | 38.2 | ||
man.4 | speC-spd1 | 1263 | 1322 | 40.7 | 38.2 | ||
man.5 | none | 1764 | 1779 | 12.3 | 36.9 | ||
M6, MGAS10394 | |||||||
10394.1 | sdn | 0020 | 0068 | 39.9 | 39.7 | ||
10394.2 | speA4 | 0733 | 0741 | 8.8 | 32.2 | ||
10394. 3 | speK-sla | 0982 | 1026 | 33.2 | 38.0 | ||
10394.4† | mef(A), R6 | 1123 | 1173 | 58.9 | 38.2 | ||
10394.5 | speC-spd1 | 1194 | 1242 | 31.9 | 38.4 | ||
10394.6 | sda | 1338 | 1366 | 24.5 | 40.4 | ||
10394.7 | spd3 | 1540 | 1562 | 21.1 | 39.5 | ||
10394.8 | none | 1804 | 1824 | 13.9 | 36.6 | ||
M12, MGAS2096 | |||||||
2096.1 | speC-spd1 | 0553 | 0602 | 41.3 | 39.1 | ||
2096-RD.1 | srtA | 0869 | 0890 | 17.5 | 31.9 | ||
2096-RD.2 | tet(O) | 1103 | 1159 | 63.0 | 43.1 | ||
2096.2 | sda | 1440 | 1492 | 40.8 | 39.8 | ||
M12, MGAS9429 | |||||||
9429.1 | speC-spd1 | 0532 | 0594 | 41.3 | 38.0 | ||
9429.2 | speH-speI | 0795 | 0851 | 17.5 | 38.1 | ||
9429-RD.1 | srtA | 0911 | 0934 | 63.0 | 31.9 | ||
9429.3 | sda | 1415 | 1468 | 40.8 | 39.8 | ||
M18, MGAS8232 | |||||||
8232.1 | speA1 | 0336 | 0394 | 39.0 | 37.7 | ||
8232.2 | speC-spd1 | 0716 | 0779 | 41.1 | 38.2 | ||
8232.3 | speL-speM | 1238 | 1309 | 46.7 | 37.6 | ||
8232.4 | spd3 | 1444 | 1506 | 38.4 | 37.7 | ||
8232.5 | sda | 1745 | 1808 | 41.8 | 38.5 | ||
M28, MGAS6180 | |||||||
6180-RD.0 | srtA | 0771 | 0793 | 17.5 | 31.9 | ||
6180.1 | speC-spd1 | 0967 | 1033 | 46.3 | 37.2 | ||
6180-RD.1 | none | 1079 | 1089 | 11.1 | 30.7 | ||
6180.2 | speK-sla | 1220 | 1285 | 42.3 | 38.4 | ||
6180-RD.2 | R28 | 1302 | 1337 | 36.3 | 35.0 | ||
6180.3 | none | 1789 | 1813 | 14.3 | 36.8 | ||
6180.4 | none | 1840 | 1864 | 11.8 | 36.6 |
There are no known or obvious virulence genes.
Element 10394.4 is chimeric, composed of a phage-like 5′ end and an ICE-like 3′end.