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. Author manuscript; available in PMC: 2008 Apr 25.
Published in final edited form as: Neuroscience. 2007 Feb 28;146(1):98–107. doi: 10.1016/j.neuroscience.2007.01.043

Figure 3.

Figure 3

Accumulation of cerebral Aβ in young and older Tg-SwDI mice. (A) ELISA measurements of total Aβ 40 (gray bars) and Aβ 42 (black bars) in mouse forebrain tissue. (B) ELISA measurements of soluble Aβ (gray bars) and insoluble Aβ (black bars) in mouse forebrain tissue. ELISA data shown are mean ± S.D. (n = 6 mice per age group). *P < 0.000001, **P < 0.0001. (C) Representative dot blot analysis of Aβ oligomers in soluble mouse forebrain extracts. (D) Quantitation of soluble Aβ oligomers from dot blots of young and older Tg-SwDI mice. Data shown are mean ± S.D. (n = 6 mice per age group). *P < 0.0002.