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. Author manuscript; available in PMC: 2007 Aug 15.
Published in final edited form as: Neuron Glia Biol. 2006 Nov;2(4):259–269. doi: 10.1017/S1740925X07000403

Fig. 1. Spinal infusion of astroglial toxin alpha-aminoadipate (L-α-AA) blocks neuropathic pain.

Fig. 1

L-α-AA (10, 50, 150 nmol) was injected intrathecally 10 days after SNL. Mechanical allodynia, a major feature of chronic pain, is dose-dependently suppressed by the toxin. *, P<0.05; **, P<0.01, compared to vehicle (saline) control; ANOVA; n=6. Mechanical allodynia was tested using von Frey hairs. Reproduced, with permission, from (Zhuang et al., 2006a).