Table 2. Performance for the different alleles in terms of the Pearsons correlation for the “leave-one-out” experiment with added random negatives.
(A) Predictors of HLA-A locus molecules (with random negatives) | |||||||
Pan | Self | Neighbor | Supertype | Count | |||
A0101 | 0.46 | 0.88 | 0.26 | A1101 | A1 | 1213 | |
A0201 | 0.87 | 0.89 | 0.82 | A0206 | A2 | 3876 | |
A0202 | 0.81 | 0.81 | 0.74 | A0203 | 0.76 | A2 | 1447 |
A0203 | 0.87 | 0.89 | 0.83 | A0202 | 0.82 | A2 | 2046 |
A0206 | 0.79 | 0.82 | 0.76 | A0201 | 0.76 | A2 | 2055 |
A0211 | 0.63 | 0.39 | 0.47 | A0201 | 0.47 | A2 | 141 |
A0212 | 0.85 | 0.59 | 0.73 | A0201 | 0.73 | A2 | 113 |
A0216 | 0.76 | 0.31 | 0.52 | A0201 | 0.52 | A2 | 57 |
A0219 | 0.75 | 0.57 | 0.59 | A0212 | 0.61 | A2 | 137 |
A0301 | 0.79 | 0.84 | 0.76 | A1101 | A3 | 2488 | |
A1101 | 0.84 | 0.87 | 0.80 | A0301 | 0.80 | A3 | 2247 |
A2301 | 0.77 | 0.71 | 0.76 | A2402 | 0.58 | A24 | 167 |
A2402 | 0.81 | 0.85 | 0.78 | A2301 | 0.71 | A24 | 418 |
A2403 | 0.83 | 0.84 | 0.82 | A2402 | A24 | 321 | |
A2601 | 0.69 | 0.79 | 0.53 | A2602 | A26 | 1032 | |
A2602 | 0.71 | 0.69 | 0.70 | A2601 | 0.70 | A26 | 76 |
A2902 | 0.69 | 0.86 | 0.07 | A3101 | 0.53 | A3 | 160 |
A3001 | 0.68 | 0.82 | −0.11 | A3002 | 0.68 | A3 | 931 |
A3002 | 0.65 | 0.64 | 0.37 | A3001 | 0.36 | A1 | 92 |
A3101 | 0.77 | 0.84 | 0.62 | A3301 | 0.53 | A3 | 2123 |
A3301 | 0.66 | 0.76 | 0.56 | A3101 | 0.09 | A3 | 1140 |
A6801 | 0.62 | 0.80 | −0.05 | A6802 | 0.28 | A3 | 1141 |
A6802 | 0.74 | 0.78 | 0.60 | A6901 | 0.31 | A2 | 1434 |
A6901 | 0.76 | 0.81 | 0.72 | A6802 | 0.62 | A2 | 1648 |
Ave | 0.74 | 0.75 | 0.57 | ||||
Ave ex supertypes | 0.75 | 0.73 | 0.57 | 0.57 | Sum | 26503 | |
(B) Predictors of HLA-B locus molecules (with random negatives) | |||||||
Pan | Self | Neighbor | Supertype | Count | |||
B0702 | 0.55 | 0.88 | 0.53 | B0801 | B7 | 1572 | |
B0801 | 0.62 | 0.75 | 0.53 | B0802 | B8 | 812 | |
B0802 | 0.59 | 0.86 | 0.76 | B0801 | 0.76 | B8 | 724 |
B1501 | 0.41 | 0.83 | 0.37 | B3501 | B62 | 1284 | |
B1801 | 0.76 | 0.85 | 0.30 | B3501 | 0.28 | B62 | 290 |
B2705 | 0.05 | 0.82 | 0.15 | B4002 | B27 | 1257 | |
B3501 | 0.68 | 0.79 | 0.63 | B5301 | 0.48 | B7 | 982 |
B3901 | 0.48 | 0.71 | 0.24 | B0801 | B39 | 81 | |
B4001 | 0.59 | 0.82 | 0.55 | B4002 | B44 | 1257 | |
B4002 | 0.82 | 0.75 | 0.68 | B4001 | 0.68 | B44 | 118 |
B4402 | 0.80 | 0.70 | 0.77 | B4403 | 0.29 | B44 | 119 |
B4403 | 0.79 | 0.74 | 0.70 | B4402 | 0.43 | B44 | 119 |
B4501 | 0.54 | 0.73 | 0.50 | B4402 | 0.12 | B44 | 114 |
B5101 | 0.58 | 0.79 | 0.57 | B5301 | 0.40 | B7 | 244 |
B5301 | 0.75 | 0.79 | 0.69 | B3501 | 0.43 | B7 | 254 |
B5401 | 0.57 | 0.80 | 0.36 | B0702 | 0.36 | B7 | 255 |
B5701 | 0.68 | 0.72 | 0.69 | B5801 | 0.69 | B58 | 59 |
B5801 | 0.45 | 0.85 | 0.66 | B5701 | B58 | 1340 | |
Ave | 0.59 | 0.79 | 0.54 | ||||
Ave ex supertypes | 0.69 | 0.78 | 0.61 | 0.45 | Sum | 10881 |
Performance values for the “leave-one-out” experiment with added random negatives. (A) shows the performance for the 24 HLA-A alleles, and (B) the performance for the 18 HLA-B alleles. The first column gives the allele name, the following columns the performance of the Pan, Self, Neighbor, and Supertype methods, respectively, as explained in the text. After the Neighbor and Supertype performance values is shown the neighbor allele name and supertype association, respectively. Note, that the supertype performance is only stated for the non-supertype representing alleles. The final column gives the number of peptide data for each allele.