Table 3. Performance of the pan-specific binding predictors.
ANN | HLA-A | HLA-B |
NetMHCpan | 0.77 | 0.77 |
Self | 0.75 | 0.79 |
The average performance per locus of the pan-specific NetMHCpanA and –panB predictors vs. single allele specific ANN's trained using only data from available self-HLA molecules. Training and validation is done in a conventional cross-validated manner as described in Materials and methods with added random natural negative peptides.