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Biotransformation of 7-hydroxyisoflavone (2a) and 7,4′-dihydroxyisoflavone (2b). (A) Biotransformation of 7-hydroxyisoflavone by BphA and BphB. Compounds: 1, isoflavonoid 2a; 2, DHD; 3, 7,3′4′-trihidroxysoflavone. (B) Biotransformation of 7,4′-dihydroxyisoflavone by BphA. Compounds: 1, isoflavonoid 2b; 2, compound in brackets denotes a proposed unstable intermediate; 3, 7,2′4′-trihydroxyisoflavone.
