Figure 4.

The effect of neutralization of individual endogenous β-chemokines on HIV replication in tetanus toxoid-stimulated CD8-depleted PBMCs from HIV-infected individuals. CD8-depleted PBMCs from three HIV-infected subjects were stimulated with tetanus toxoid in the presence of isotype control antibody (50 μg/ml) or anti-MIP-1α (50 μg/ml), anti-MIP-1β (50 μg/ml), or anti-RANTES (10 μg/ml). Culture supernatants were assayed for the levels of reverse transcriptase activity or p24 antigen at various time points during the culture period.