TABLE 3.

Effects of enzyme inhibitors on the CL-20 biotransformation activity of a membrane-associated enzyme(s)^c

Inhibitor (2 mM)	% CL-20 biotransformation activitya
None (control)	100 ± 1.7
Diphenyliodonium	38 ± 2.3
Dicumarol	86 ± 3.5
Metyrapone	91 ± 2.8
Carbon monoxideb	87 ± 2.2
2,2-Dipyridyl	92 ± 3.4

^aOne hundred percent CL-20 biotransformation activity was equivalent to 11.5 nmol h⁻¹ mg of protein⁻¹. Data are mean percentages of CL-20 biotransformation activity ± standard errors (n = 3).

^bCarbon monoxide was bubbled through the aqueous phase and headspace for 60 s in sealed vials.

^cThe CL-20 biotransformation activity of the membrane-associated enzyme(s) (1 mg/ml) was determined at pH 7.0 and 30°C after 1 h under anaerobic conditions.