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. Author manuscript; available in PMC: 2008 Jul 1.
Published in final edited form as: Brain Behav Immun. 2006 Oct 31;21(5):569–580. doi: 10.1016/j.bbi.2006.09.001

Figure 5.

Figure 5

Clonidine’s effects and BRL44408 reversal of clonidine’s effects in lymphocytes, TGF-β1 (TGF), anti-inflammatory macrophages and Th-1 type lymphocytes in sciatic nerve 24 hr after treatments. A. Immunostaining of STAT4, CD2 and co-localization of both (arrow heads) in the sciatic nerve 24 hr after zymosan plus saline (upper panel, ZYM+SAL), zymosan plus clonidine (middle panel, ZYM+CLO) and zymosan plus BRL44408 plus clonidine group (lower panel, Z+BR+CL). B. Immunostaining of ED1, TGF-β1 and co-localization of both (arrow heads) in the sciatic nerve 24 hr after zymosan plus saline (upper panel) zymosan plus clonidine (middle panel) and zymosan plus BRL44408 plus clonidine group (lower panel). Scale bar = 50 μm.