Table II.

Effects of various flavonoids on genistein transport

Plasma membrane vesicles were incubated with 50 μm genistein and 5 mm MgATP in the absence (control) or presence of 250 μm of the flavonoids indicated. Values shown are mean ± sd of three replicates, and asterisks indicate a statistically significant difference compared to the +MgATP control. **, P < 0.01; *, P < 0.05.

Compound	Substance Class	Genistein Uptake
		%
Control		100
Daidzein	Isoflavone	29.0 ± 6.5**
Biochanin A	Isoflavone	32.1 ± 4.1**
Formononetin	Isoflavone	29.7 ± 6.3**
Naringenin	Flavanone	88.9 ± 13.7
Kaempferol	Flavonol	74.0 ± 7.7
Genistin	7-O-glucoside of genistein	55.9 ± 5.4*
Daidzin	7-O-glucoside of daidzein	88.4 ± 9.6
Naringin	7-O-glucoside of naringenin	89.5 ± 10.7