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. Author manuscript; available in PMC: 2007 Sep 20.
Published in final edited form as: Neuron. 2007 Mar;53(5):677–687. doi: 10.1016/j.neuron.2007.02.005

Figure 3.

Figure 3

Mean (± SEM) phase angles of activity onsets in wild-type and MW-coneless mice (see figure 2b for individual data). In both genotypes (n=8), the number of days to achieve a stable phase angle of entrainment increases as the light intensity during the light phase decreases Wild-type mice achieve stable re-entrainment (phase angle = 0 hr) after the shift from 100 to 10 lux and from 10 to 1 lux (respectively 14.7 ± 2 and 23.2 ± 1.1 days). In contrast, MW-coneless (TRβ−/−) mice re-entrain with an abnormal phase angle (1.91 ± 0.04 hr, ANOVA, p<0.001) after 21.3 ± 1.1 days for the decrease from 100-10 lux (Mann-Whitney U test; p<0.05) and when the light level is decreased to 1 lux still do not display a stable phase angle of entrainment at least after 43 days.