Figure 1. Identification of DNaseI HS Sites from Six Cell Types.
(A) Representative DNase-chip data from ENCODE region ENr231 (Chr1:148050000–148165000). Note that there are common, ubiquitous, and cell type–specific DNaseI HS sites.
(B) DNase-chip from K562 cells identifies all five LCR DNaseI HS sites upstream of the β-globin locus, as well as the 3′ DNaseI HS site (in red). There are additional DNaseI HS sites identified around promoter regions of the globin genes.