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. 2007 Jul 31;4(7):e237. doi: 10.1371/journal.pmed.0040237

Figure 4. KGF and Leptin in Human Fetal Lungs.

Figure 4

ELISAs were performed on the lungs of 20 fetuses with nonpulmonary diseases used as controls, ranging from 14 to 37 wk of pregnancy, and on 11 fetuses with CDH ranging from 22 to 37 wk. Individual values are shown. Linear regression was performed for the period 22–37 wk when samples were available for both groups. KGF (A) displayed different profiles according to the groups concerned, with a negative slope for control lungs and a positive slope for CDH lungs (−1.17 versus 2.23, respectively, p = 0.03). Leptin assay (B) evidenced little change in control lungs before 22 wk; a similar linear increase occurred between 22 and 37 wk with no difference between groups (slope = 4.82 versus 2.60 for controls and CHD samples, respectively, p = 0.18).