Table 4.

Summary of RBP4 Association with Intravenous Glucose Tolerance Test Measures

Population	SNP	N	Genotype Counts	SI	AIRG	DI
Af. Am.	+759	119	30/57/32	0.51	0.49	0.96
Af. Am.	+848	118	103/15/0	0.62	0.77	0.97
Af. Am.	+3681	118	87/31/0	0.97	0.026	0.081
Af. Am.	+7019	119	96/23/0	0.98	0.5	0.33
Af. Am.	+7803	118	73/38/7	0.45	0.48	0.17
Af. Am.	+9476	119	46/60/13	0.11	0.41	0.093
Af. Am.	+11881	119	41/60/18	0.83	0.88	0.91
UT Cauc	-804	122	81/41/4*	0.75	0.0098	0.022
UT Cauc	+390	122	106/20/0	0.2	0.86	0.88
UT Cauc	+759	122	36/70/20	0.98	0.93	0.66
UT Cauc	+9476	122	77/41/4*	0.45	0.0011	0.067
UT Cauc	+10350	122	101/21/0	0.44	0.13	0.1
AR Cauc	-804	208	149/57/2*	0.63	0.1	0.46
AR Cauc	+390	208	183/25/0	0.0005	0.5	0.005
AR Cauc	+759	208	86/95/27	0.58	0.51	0.32
AR Cauc	+9476	208	148/55/5*	0.64	0.039	0.29
AR Cauc	+10350	207	181/26/0	0.91	0.11	0.21

Table 4 gives the p values for the difference between marginal means by genotype. P values are presented without correction for multiple testing of traits and SNPs, which are strongly correlated. Marginal means for genotypes showing nominally significant differences among genotypes are shown in Table 5. Af. Am., Arkansas African American metabolic study; UT Cauc, Utah Caucasian metabolic study; AR Cauc, Arkansas Caucasian Metabolic study; N, number of successfully typed samples; genotype counts, counts of common homozygotes/heterozygotes/rare homozygotes; S_I, insulin sensitivity index from MinMod; AIR_G, acute 2-10 min insulin response to intravenous glucose bolus; DI, disposition index, S_I*AIR_G.

^*, genotypes rescored to include rare homozygotes with heterozygotes for analysis.