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. Author manuscript; available in PMC: 2008 Apr 30.
Published in final edited form as: Dev Cell. 2007 May;12(5):727–738. doi: 10.1016/j.devcel.2007.02.011

Figure 7. Coordinated cytoskeletal activity and the symmetry of Baz/AJs positioning.

Figure 7

Projections of deconvolved confocal stacks of WT embryos at gastrulation (A, C, E, G) and during germband extension (B, D, F, H) are shown. (A, B) Treatment with carrier alone had no effect on Baz/AJ (DE-Cad) positioning. Baz develops some planar polarity (arrow). (C, D) Disruption of MTs with colchicine had minimal effects of Baz/AJ positioning. (E, F) Disruption of actin with cytochalasin D produced enhanced planar polarity of both Baz and DE-Cad at both stages. (G, H) Simultaneous treatment with cytochalasin D and colchicine resulted in a relatively symmetric distribution of Baz and DE-Cad at both stages. Bar, 5 μm. (I) A model of aPKC regulation of MT organization, AJ positioning and epithelial structure during development.

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