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. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Dev Biol. 2006 Aug 10;300(1):434–460. doi: 10.1016/j.ydbio.2006.08.007

Figure 6.

Figure 6

Neighbor joining tree of the 14 synaptotagmin isoforms in S. purpuratus. Alignments of the C2A-C2B domains were made using ClustalW, numbers indicate bootstrap values (1000 replicates). For this analyis, the extra N-terminal C2 domain in SPU_16698 (Sp-Syt15-1-5P) and the two C-terminal C2 domains in SPU_28132 (Sp-Syt15-1-3P), were treated as different genes rather than alleles. The predicted amino acid sequence for Sp-Syt1-1 derived from cDNA (AAB67801) was used instead of SPU_005854, as this gene model is missing part of the C2B region.