Figure 1.

Kinetics of luciferase imaging. Hollow fibers filled with MCF7-Luc-10C11 cells stably expressing luciferase at 5 x 10⁶ cells/ml (60,000 cells/fiber) were implanted into nude mice in both flanks. (A) Twenty-four hours later, sequential bioluminescence images were acquired at 5-minute intervals after luciferin administration (90 mg/kg, i.p.). (B) Quantitative analysis of sequential images expressed as photons per second. Each time point represents 10 hollow fibers implanted from five mice (error bars represent the standard error of the mean).