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. Author manuscript; available in PMC: 2008 Jul 1.
Published in final edited form as: Methods. 2007 Jul;42(3):278–288. doi: 10.1016/j.ymeth.2007.02.005

Scheme 1.

Scheme 1

Synthesis of the N-derivatized oxalylaminoindole inhibitors, compound panel 2a-2k. Compound 4 was synthesized in five steps essentially as described [39]. Reaction conditions: (a) NaH (1.3 equiv), DMF, RX; (á) NaH (3.0 equiv), DMF, RX; (b) ethyl oxalyl chloride, THF; (c) 1.NaOH, H2O, EtOH; 2. HCl.