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. 2007 Jun 25;35(14):4664–4677. doi: 10.1093/nar/gkm483

Figure 1.

Figure 1.

The proposed XIAP IRES RNA secondary structure model. The sites sensitive to RNase T1, which cuts after single-stranded guanine nucleotides, RNase T2, which cuts after single-stranded nucleotides, and RNase V1, which cuts within regions of double-stranded RNA, are shown on the derived structural model. These cut sites were used as constraints in the MFOLD (44) program to predict the secondary structure of the minimal XIAP IRES sequence. The full list of sensitive sites is shown in Supplementary Table 1.