Figure 5.
Down-regulation of β-gal expression of CT26.CL25 pulmonary metastases. In a second survival experiment (data not shown) mice were inoculated with 2×107 tumor cells and treated 3 and 10 days later with 2×107 p.f.u. i.v. with the relevant virus. When mice died their lungs were removed and stained for β-gal expression as described in Materials and Methods. (A) Mouse inoculated with CT26.WT and treated with MVA-LZ, (B) mouse inoculated with CT26.CL25 and treated with FPV, (C) mouse inoculated with CT26.CL25 and treated with MVA-LZ