Table 4. .
The 40 Proteins Associated with the 20 Polygenic Diseases
| Disease Name | Proteins |
| Autosomal recessive osteopetrosis (OPTB1 [MIM 259700]) | CLCN7_HUMAN and VPP3_HUMAN |
| Crohn disease (CD [MIM 266600]) | CAR15_HUMAN and IL10_HUMAN |
| Dejerine-Sottas syndrome (DSS [MIM 145900]) | MYP0_HUMAN and PMP22_HUMAN |
| Epidermolysis bullosa simplex Dowling-Meara type (DM-EBS [MIM 131760]) | K1C14_HUMAN and K2C5_HUMAN |
| Epidermolysis bullosa simplex Koebner type (K-EBS [MIM 131900]) | K1C14_HUMAN and K2C5_HUMAN |
| Fast-channel congenital myasthenic syndrome (FCCMS [MIM 608930]) | ACHA_HUMAN, ACHD_HUMAN, and ACHE_HUMAN |
| Glanzmann thrombasthenia (GT [MIM 273800]) | ITA2B_HUMAN and ITB3_HUMAN |
| Isolated growth hormone deficiency type IB (IGHD IB [MIM 262400]) | GHRHR_HUMAN and SOMA_HUMAN |
| Juvenile polyposis syndrome (JPS [MIM 174900]) | BMR1A_HUMAN and SMAD4_HUMAN |
| LS | ATP6_HUMAN, DHSA_HUMAN, and SURF1_HUMAN |
| Leukoencephalopathy with vanishing white matter (VWM [MIM 603896]) | EI2BA_HUMAN, EI2BB_HUMAN, EI2BD_HUMAN, and EI2BE_HUMAN |
| Li-Fraumeni syndrome (LFS [MIM 151623]) | CD2A1_HUMAN and P53_HUMAN |
| Loeys-Dietz aortic aneurysm syndrome (LDAS [MIM 609192]) | TGFR1_HUMAN and TGFR2_HUMAN |
| Lung cancer (MIM 211980) | BRAF1_HUMAN and EGFR_HUMAN |
| OI-II | CO1A1_HUMAN and CO1A2_HUMAN |
| OI-IV | CO1A1_HUMAN and CO1A2_HUMAN |
| Pachyonychia congenita type 1 (PC1 [MIM 167200]) | K1C16_HUMAN and K2C6A_HUMAN |
| Pachyonychia congenita type 2 (PC2 [MIM 167210]) | K1C17_HUMAN and K2C6B_HUMAN |
| Sitosterolemia (MIM 210250) | ABCG5_HUMAN and ABCG8_HUMAN |
| Tuberous sclerosis complex (TSC [MIM 191100]) | TSC1_HUMAN and TSC2_HUMAN |