Figure 2. .

Effects of miR-155 on the luciferase reporter genes bearing 3′ UTR segments from hAGTR1 3′-UTR. 293T cells were cotransfected with pTAL-Luc hAGTR1 3′-UTR 1166A or pTAL-Luc hAGTR1 3′ UTR 1166C, pTAL-Luc hAGTR1 3′ UTR deletion 1163–1169, and different concentrations (20, 10, or 2.5 nM) of miR-155 (white bars) or no miRNA (black bars) or 20 nM of Let-7c (unrelated miRNA [dashed lines]). Values are means of firefly/Renilla ratio from three independent experiments (each with three culture replicates). Error bars indicate 1 SD of three independent experiments. P values were calculated from a two-sided, two-sample t test.