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. 2007 Jul 27;81(3):596–606. doi: 10.1086/519980

Table 2. .

Two-Point LOD Scores (Z) for Linkage between the Cataract Locus and Markers on Chromosome 20q Listed in Physical Order (Mb) from the Short-Arm Telomere (p-tel)[Note]

Distance from p-tel
Za at θ =
Marker cM Mb .00 .05 .10 .20 .30 .40 Zmax θmax
D20S885 39.9 17.91 −7.79 2.51 2.72 2.35 1.60 .74 2.72 .10
D20S111 49.2 29.94 −2.82 1.14 1.17 .91 .54 .19 1.18 .08
D20S837 50.7 30.73 −.81 4.15 3.98 3.18 2.14 1.01 4.15 .05
rs2057262 31.15 −4.03 −.02 .14 .16 .09 .03 .17 .15
D20S195 50.2 31.29 3.65 4.17 3.88 2.96 1.90 .87 4.20 .03
CHMP4B (A>T) 31.90 6.24 5.87 5.37 4.19 2.82 1.36 6.24 .00
D20S909 50.7 33.92 1.89 1.88 1.72 1.25 .73 .33 1.91 .02
D20S896 50.2 34.16 2.88 2.60 2.30 1.68 1.05 .46 2.88 .00
D20S870 50.7 34.16 3.11 2.93 2.63 1.94 1.23 .59 3.11 .00
D20S847 50.2 34.32 5.50 5.18 4.72 3.60 2.33 1.05 5.50 .00
rs1291139 34.95 −1.85 .99 1.10 .96 .66 .30 1.10 .11
D20S834 50.7 35.43 −1.08 2.07 1.91 1.30 .65 .19 2.07 .05
D20S607 54.9 38.23 −1.61 1.85 2.02 1.81 1.30 .66 2.03 .11
D20S855 56.0 39.08 −.29 3.26 3.19 2.58 1.71 .77 3.27 .06

Note.— STR marker allele frequencies used for linkage analysis were those calculated by Généthon/Marshfield/deCODE. A gene frequency of .0001 and a penetrance of 95% were assumed for the disease locus.

a

Z values were calculated using the MLINK subprogram from the LINKAGE (5.1) package of programs.34