Figure 5.

Human LS amplification of the aquaporin 7 (AQP7) gene relative to other primates. (A) Human chromosome 9 is shown with the Treeview image corresponding to 9p22–9q22. The Treeview image depicts the aCGH log₂ fluorescence ratio in pseudocolor as shown, with green and red signals indicative of a copy number decrease and increase, respectively, relative to human. Each cDNA is ordered according to human genome position. All individuals from one species are color-coded as shown. The red dots signify locations of AQP7-related cDNAs. (B) Enlarged Treeview image for the region adjacent to the C-band that includes five copies of AQP7. (C) The graph shows the aCGH log₂ fluorescence ratio (red) plotted against the Q-PCR values (green) for the AQP7 gene for 10 primate species. The correlation coefficient for the two data sets is r² = 0.9532.