Table 1.

Protein domains identified through mutation enrichment analysis

^aDomains wth Group CaMP scores or CaMP GSEA scores >1 were considered significant. The false discovery rates for each of these approaches is estimated to be 10% (see Methods for details).

^bThe composite score was determined to be the product of the sum of the Group CaMP and CaMP GSEA scores and the fold change of the gene enrichment.