Figure 4. Quantification of the direction of interneuronal migration in the embryonic cortex.

(A–C) Neurons migrating in four distinct directions (towards the pial surface, towards the ventricular surface, tangentially towards cortex [subpallium→ pallium], tangentially towards ganglionic eminence [pallium→ subpallium]) within the cortical plate (A), intermediate zone (B), and ventricular zone (C) were measured. Surprisingly, significant numbers of interneurons across the cerebral wall migrate in cortex→ ganglionic eminence direction. Number of cells/group>1500. Data shown are mean±SEM.