Table 2. .
Position |
Genome Scan of theNSCL/P-Affected Family |
||||
Nonparametric LOD |
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SNP | Genetic (cM) |
Physical (bp) |
Parametric LOD | NPL | P |
rs726131 | 65.641 | 42,118,566 | −.55 | 10.53 | .000656 |
rs1824683 | 66.057 | 42,403,918 | 3.48 | 34.40 | .000244 |
rs328149 | 66.087 | 42,424,469 | 3.51 | 36.10 | .000244 |
rs645631 | 66.203 | 42,505,993 | 3.61 | 42.82 | .000153 |
rs1073744 | 66.204 | 42,506,272 | 3.61 | 42.81 | .000153 |
rs953291 | 67.077 | 43,124,497 | 3.61 | 42.78 | .000153 |
rs1944574 | 68.548 | 43,979,261 | 3.61 | 42.82 | .000153 |
rs953570 | 68.567 | 43,988,463 | 3.61 | 42.82 | .000153 |
rs1944584 | 68.667 | 44,035,980 | 3.61 | 42.82 | .000153 |
rs1398193 | 68.885 | 44,241,137 | 3.61 | 42.83 | .000153 |
rs1877412 | 68.885 | 44,241,673 | 3.61 | 42.83 | .000153 |
rs1943984 | 70.873 | 45,477,909 | 3.61 | 42.76 | .000153 |
rs1985467 | 71.431 | 45,928,259 | 3.61 | 42.82 | .000153 |
rs1822466 | 71.519 | 45,999,664 | 3.61 | 42.83 | .000153 |
rs1373185 | 71.519 | 45,999,849 | 3.61 | 42.83 | .000153 |
rs768360 | 71.542 | 46,018,071 | 3.61 | 42.83 | .000153 |
rs2006747 | 71.795 | 46,222,356 | 3.61 | 42.83 | .000153 |
rs728682 | 71.966 | 46,349,352 | 3.61 | 42.83 | .000153 |
rs2969972 | 71.989 | 46,362,761 | 3.61 | 42.84 | .000061 |
rs1822458 | 72.264 | 46,528,403 | 3.61 | 42.94 | .000061 |
rs1941962 | 72.892 | 46,999,467 | 3.61 | 43.17 | .000061 |
rs1369766 | 73.228 | 47,272,878 | 3.61 | 43.30 | .000061 |
rs728683 | 73.339 | 47,362,995 | 3.61 | 43.33 | .000061 |
rs724349 | 74.247 | 48,019,014 | 2.92 | 17.33 | .000244 |
rs959655 | 74.477 | 48,132,862 | .23 | 10.74 | .000610 |
rs768207 | 74.477 | 48,132,968 | −.04 | 10.73 | .000610 |
Note.— The model used for parametric analysis was incomplete dominance with 65% penetrance and a disease-allele frequency of .0001.