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. Author manuscript; available in PMC: 2008 Apr 30.
Published in final edited form as: J Neuroimmunol. 2007 Apr 27;186(1-2):86–93. doi: 10.1016/j.jneuroim.2007.03.014

Figure 1.

Figure 1

sPECAM-Fc blocks migration of lymphocytes across an in vitro murine brain endothelial cell monolayer. Lymphocytes were incubated for four hours in QCM™ 24-well Invasion Assay chambers with endothelial cell monolayers in the presence of 20 μg/ml sPECAM-Fc or human IgG-Fc. Migrated cells were collected, washed, and counted as described in Material and Methods. In the presence of sPECAM-Fc, on average, 2.4 times fewer cells migrated across the monolayers. Error bars represent the standard deviation. p < 0.02 Double size diamonds indicate a second measurement of the same magnitude.