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. Author manuscript; available in PMC: 2007 Nov 1.
Published in final edited form as: Dev Biol. 2006 Jul 21;299(1):137–150. doi: 10.1016/j.ydbio.2006.07.016

Figure 9. PSA removal with endo-N prevents BMP induced delays in NCC migration through the colon.

Figure 9

(A–D) E11.5 gut explants were maintained in culture for 48 hours (A) under control conditions, or with (B) endo-N, (C) BMP4, or (D) BMP4 plus endo-N. Endo-N did not affect NCC migration under control conditions, but prevented the delay in NCC migration induced by BMP4. White lines indicate the end of the colon. Ce = cecum. (E) Quantitative analysis of colon innervation (n = 10 explants for each treatment). Scale bar = 100 μm. Landmarks for these measurements are in Figure 4F.