Fig. 1.
A transverse view of a Chlamydomonas flagellum as viewed looking proximal to distal; the outer doublet microtubules are numbered according to Hoops and Witman [1983]. The direction of the effective stroke is indicated by the arrow. Only doublet number one lacks an outer dynein arm. A single doublet microtubule (doublet one) with associated radial spoke, as well as the entire central apparatus, is enlarged. The radial spoke diagram is further enlarged to include details of the possible location of particular radial spoke components. RSP2 serves as the primary stalk component and consists of GAF domains as well as calmodulin (CM) binding domains [Yang et al., 2002]. The central apparatus diagram is adapted from Mitchell and Sale [1999]. While PF6, PF16, PP1c, AKAP240, KRP, and KLP1 have been tentatively localized to specific central tubules (see Table I), it is unknown whether they localize to specific projections. Therefore, they are listed above the central apparatus diagram. For references, see Table I.