Figure 4. Sensitivity of Viruses to Neutralization by MAbs.
Luciferase reporter viruses pseudotyped with parental, mutant, or adapted Envs as indicated were incubated with various concentrations of the MAbs (A) IgG b12, (B) 4E10, or (C) 17b for 1 h prior to infection of 293.CD4.CCR5 cells. The amount of luciferase activity obtained for each virus pseudotype in the absence of any antibody was set to 100%. The results shown are the average for three independent experiments, ± standard error of the mean.