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. 2007 Aug 24;3(8):e117. doi: 10.1371/journal.ppat.0030117

Figure 5. Relative Sensitivity of Parental, Mutant, and Adapted Envs to Entry Inhibitors.

Figure 5

Pseudotyped luciferase reporter viruses were used to determine sensitivity to the fusion inhibitor (A) enfuvirtide, or the CCR5 inhibitors (B) aplaviroc, (D) AD101, and (F) CMPD167. Sensitivity of Envs to (C) aplaviroc, (E) AD101, and (G) CMPD167 was determined in a cell–cell fusion luciferase reporter assay, using QT6 effector cells expressing the indicated Env and QT6 target cells expressing CD4 and CCR5. Results are the average of three or four independent experiments, ± standard error of the mean.