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Synthesis of various l-amino acids from the corresponding d-amino acid amides by LaaA in the presence of ACL racemase
| Substrate | Product | Yield (%)a | ee (%) |
|---|---|---|---|
| d-Alanine amide | l-Alanine | 100b | >99 |
| d-Leucine amide | l-Leucine | 100c | >99 |
| d-Methionine amide | l-Methionine | 100c | >99 |
Concentration in the reaction mixture.
Synthesized for 12 h using LaaA (0.45 mg) and ACL racemase (10 mg).
Synthesized for 20 h using LaaA (0.45 mg) and ACL racemase (0.13 mg).
