FIG. 6.

Induction of antibody response with rBCG-P expressing HIV-1 gp120 in BALB/c mice with combinations of immunogen formulations. To evaluate the immunogenicity in mice of the rBCG-P expressing CON6 Env proteins, mice were immunized once with either killed or live rBCG-P/120secPas with or without IFA. The geometric mean endpoint titers (± standard errors of the means) for each group of mice (n = 5 per group) are shown. Abbreviations: 120secPas, rBCG-P expressing HIV-1 CON6 gp120 as the secreted protein; CON6, recombinant CON6 gp140CF protein.