TABLE 2.
Number of cured and relapsed patients after suramin treatment as a function of pretreatment test results, P value, and OR with 95% CI for association of test results with occurrence of relapse
| Parameter | No. of patients
|
Pa | OR (95% CI) | |
|---|---|---|---|---|
| Cured | Relapsed | |||
| Intrathecal IgM synthesis (n = 57): | ||||
| Absent | 41 | 3 | ||
| Present (IgMIF > 0%) | 3 | 10 | 0.0000015 | 46 (8.0-260) |
| CSF IgM concn (n = 60) of: | ||||
| <1.9 mg/liter | 35 | 3 | ||
| ≥1.9 mg/liter | 11 | 11 | 0.0004 | 11.7 (2.7-50) |
| CSF LATEX/IgM test end titer (n = 60) of: | ||||
| <2 | 34 | 3 | ||
| ≥2 | 12 | 11 | 0.001 | 10.4 (2.5-44) |
| <4 | 40 | 8 | ||
| ≥4 | 6 | 6 | 0.024 | 5.0 (1.3-20) |
| <8 | 41 | 8 | ||
| ≥8 | 5 | 6 | 0.014 | 6.2 (1.5-25) |
| CSF IL-10 concn (n = 60) of: | ||||
| ≤10 pg/ml | 40 | 8 | ||
| >10 pg/ml | 6 | 6 | 0.024 | 5.0 (1.3-20) |
a
Calculated by Fisher's exact test.