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. 2007 Jun 1;6(8):1486–1496. doi: 10.1128/EC.00120-07

FIG. 3.

FIG. 3.

C. neoformans ability to bind to HBMEC and the relationship to their hyaluronic acid contents. (A) Hyaluronic acid ELISA. The hyaluronic acid molecules from the surfaces of C. neoformans cells were detected using a hyaluronic acid ELISA kit (Corgenix, Inc.). (B) An in vitro binding assay was performed to examine the ability of C. neoformans cells to associate with HBMEC. The CFU of C. neoformans cells binding to HBMEC in vitro was analyzed. Columns in both panels: 1, strain B-4500FO2 (wild-type CPS1); 2, strain C559 (cps1Δ); 3, strain TYCC38-602 (wild-type CAP64); 4, strain 602 (cap64); 5, strain B4476FO5 (wild-type CAP59); 6, strain TYCC33 (cap59Δ).