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Increase in sensitivities of mutants to complement-mediated killing by human serum
| Mutant examined | Increase in serum sensitivity compared witha:
|
|||
|---|---|---|---|---|
| MC58 (50%) | MC58ΔsiaD (3%) | MC58ΔsiaDΔlst (3%) | MC58ΔsiaC (3%) | |
| MC58ΔlctP | +++ | |||
| MC58ΔsiaD | +++ | |||
| MC58ΔsiaDΔlst | +++ | |||
| MC58ΔsiaC | +++ | |||
| MC58ΔsiaDΔlctP | ++ | |||
| MC58ΔsiaDΔlstΔlctP | +/− | |||
| MC58ΔsiaCΔlctP | +/− | |||
The concentrations of serum used in the assays are shown in parentheses. +++, >75%; ++, >50%; +/−, insignificant.
