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Voltage dependence of divalent ion effects for representative cells. (A) Relative conductance (extent of calcium ion block) as a function of voltage for wild-type channels with 30 mM calcium ion concentration. (B) The same plot for mutant channels. (C) Relative conductance (extent of magnesium in block) as a function of voltage for wilt-type channel with 10 mM magnesium. (D) A similar plot for the mutant channels with 30 mM magnesium.
