TABLE 1.
MIC (in μg/ml) for ciprofloxacin and levofloxacin and mutations detected in each gene of E. coli isolates
| Isolate | MIC (μg/ml) of:
|
Mutation in:a
|
||
|---|---|---|---|---|
| Ciprofloxacin | Levofloxacin | parC | parE | |
| 1 | 16 | 8 | S80I | — |
| 25 | 8 | 4 | E84K | — |
| 26 | 32 | 16 | S80I | — |
| 41 | 32 | 8 | S80I | S458A |
| 46 | 64 | 16 | S80I | S458A |
| 58 | 4 | 4 | S80I | — |
| 65 | 8 | 8 | S80I | — |
| 101 | 8 | 8 | S80I | — |
| 102 | 8 | 8 | S80I | — |
| 115 | 8 | 4 | S80I | — |
| 140 | 4 | 4 | S80R | — |
| 141 | 8 | 4 | S80R | — |
| 153 | 16 | 8 | S80I | — |
| 159 | 64 | 16 | S80I | — |
| 179 | 64 | 16 | S80I, E84V | — |
| 180 | 32 | 16 | S80I, E84G | — |
| 185 | 32 | 16 | S80I | — |
| 189 | 128 | 16 | S80I | S458A |
| 191 | 32 | 16 | S80I, A108V | — |
| 195 | 64 | 16 | S80I | S458A |
| 200 | 128 | 32 | S80I | S458A |
| 207 | 64 | 16 | S80I | S458A |
| 217 | 16 | 8 | S80I, A108V | — |
| 219 | 16 | 8 | S80I | — |
| 224 | 128 | 8 | S80I | S458A |
| 226 | 32 | 8 | S80I | S458A |
| 232 | 64 | 16 | S80I | S458A |
| 237 | 32 | 32 | S80I | — |
| 245 | 32 | 16 | S80I | S458A |
| 255 | 8 | 8 | S80I | — |
a
—, absence of mutation. All isolates had mutations resulting in S83L and D87N in gyrA and no mutation in gyrB.